| ORF |
Std. Name |
|
DCV103_C |
|
YLR373c
|
VID22 |
|
0.353
|
| Vacuole import and degradation |
|
YDR245w
|
MNN10 |
|
0.354
|
| Subunit of a Golgi mannosyltransferase complex also containing Anp1p, Mnn9p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone: membrane protein of the mannosyltransferase family |
|
YOR035c
|
SHE4 |
|
0.355
|
| Protein containing a UCS (UNC-45/CRO1/SHE4) domain, binds to myosin motor domains to regulate myosin function: involved in endocytosis, polarization of the actin cytoskeleton, and asymmetric mRNA localization |
|
YNL133c
|
FYV6 |
|
0.356
|
| Protein of unknown function, required for survival upon exposure to K1 killer toxin; proposed to regulate double-strand break repair via non-homologous end-joining |
|
YBR106w
|
PHO88 |
|
0.357
|
| Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations |
|
YNL271c
|
BNI1 |
|
0.357
|
| Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNR1 |
|
YPR120c
|
CLB5 |
|
0.358
|
| B-type cyclin |
|
YDR200c
|
VPS64 |
|
0.358
|
|
|
YOR198c
|
BFR1 |
|
0.359
|
| Multicopy suppressor of BFA (Brefeldin A)-induced lethality; implicated in secretion and nuclear segregation |
|
YML032c
|
RAD52 |
|
0.360
|
| Protein that stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis |
|
YCL016c
|
DCC1 |
|
0.361
|
| Defective in sister Chromatid Cohesion |
|
YML073c
|
RPL6A |
|
0.362
|
| N-terminally acetylated protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Bp and to rat L6 ribosomal protein: binds to 5.8S rRNA |
|
YER095w
|
RAD51 |
|
0.362
|
| Rad51p colocalizes to ~ 65 spots with Dmc1p prior to synapsis (independently of ZIP1 and DMC1), and interacts with Rad52p and Rad55p; human Rad51p homolog interacts with Brca2 protein which has been implicated in causing breast cancer|RecA homolog |
|
YGL240w
|
DOC1 |
|
0.365
|
| Processivity factor required for the ubiquitination activity of the anaphase promoting complex (APC), mediates the activity of the APC by contributing to substrate recognition: involved in cyclin proteolysis |
|
YCL029c
|
BIK1 |
|
0.366
|
| Microtubule-associated protein, component of the interface between microtubules and kinetochore, involved in sister chromatid separation: essential in polyploid cells but not in haploid or diploid cells: ortholog of mammalian CLIP-170 |
|
YGL174w
|
BUD13 |
|
0.370
|
| Protein involved in bud-site selection: diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern |
|
YLR182w
|
SWI6 |
|
0.372
|
| Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1p to regulate transcription at the G1/S transition: involved in meiotic gene expression: localization regulated by phosphorylation: potential Cdc28p substrate |
|
YBL094c
|
|
|
0.374
|
| Hypothetical ORF |
|
YDR505c
|
PSP1 |
|
0.376
|
| high-copy suppressor of cdc17 DNA polymerase alpha mutations |
|
YOR144c
|
ELG1 |
|
0.378
|
| Protein required for S phase progression and telomere homeostasis, forms an alternative replication factor C complex important for DNA replication and genome integrity: mutants are sensitive to DNA damage |
|
YGR104c
|
SRB5 |
|
0.379
|
| RNA polymerase II holoenzyme/mediator subunit |
|
YHR191c
|
CTF8 |
|
0.380
|
| Subunit of a complex with Ctf18p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion |
|
YDL115c
|
IWR1 |
|
0.381
|
| Interacts with RNA Polymerase II |
|
YHR031c
|
RRM3 |
|
0.385
|
| DNA helicase |
|
YKL204w
|
EAP1 |
|
0.386
|
| eIF4E-associated protein, binds eIF4E and inhibits cap-dependent translation, also functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade |
|
YGR092w
|
DBF2 |
|
0.387
|
| Kinase required for late nuclear division. Cdc15 promotes the exit from mitosis by directly switching on the kinase activity of Dbf2. |
|
YDR491c
|
|
|
0.387
|
| Hypothetical ORF |
|
YLR233c
|
EST1 |
|
0.391
|
| Telomere elongation protein |
|
YDR138w
|
HPR1 |
|
0.393
|
| Subunit of THO/TREX, related complexes that couple transcription elongation with mitotic recombination and elongation with mRNA metabolism and export, subunit of an RNA Pol II complex; regulates lifespan; similar to Top1p |
|
YOR080w
|
DIA2 |
|
0.400
|
| Protein of unknown function, involved in invasive and pseudohyphal growth |
|
YMR198w
|
CIK1 |
|
0.407
|
| Kar3-binding protein |
|
YDR369c
|
XRS2 |
|
0.411
|
| DNA repair protein |
|
YPR135w
|
CTF4 |
|
0.415
|
| DNA polymerase alpha binding protein |
|
YKL113c
|
RAD27 |
|
0.434
|
| 42 kDa 5' to 3' exonuclease required for Okazaki fragment processing |
|
YNL171c
|
|
|
0.436
|
| Hypothetical ORF |
|
YHR200w
|
RPN10 |
|
0.463
|
| Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome: N-terminus plays a role in maintaining the structural integrity of the RP: binds selectively to polyubiquitin chains: homolog of the mammalian S5a protein |
