SCMD Saccharomyces Cerevisiae Morphological Database
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Keywords: (ex. rad52, polarisome)

Sortable ORF Parameter Sheet

Parameter Name:DCV114_A1B
Stain Type:Nucleus
Nucleus Status:A1B
Parameter Type:Coefficient of Variation
Description:Ratio_of_D110_to_C128_on_stage_A1B
Definition:Ratio_of_D110_to_C128_on_stage_A1B
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ORF Std. Name DCV114_A1B
YMR224c MRE11 0.319
Subunit of a complex with Rad50p and Xrs2p (RMX complex) that functions in repair of DNA double-strand breaks and in telomere stability, exhibits nuclease activity that appears to be required for RMX function: widely conserved
YDL116w NUP84 0.320
nuclear pore complex subunit|similar to mammalian Nup107p
YER016w BIM1 0.321
Microtubule-binding protein that together with Kar9p makes up the cortical microtubule capture site and delays the exit from mitosis when the spindle is oriented abnormally
YDR138w HPR1 0.322
Subunit of THO/TREX, related complexes that couple transcription elongation with mitotic recombination and elongation with mRNA metabolism and export, subunit of an RNA Pol II complex; regulates lifespan; similar to Top1p
YPR164w MMS1 0.322
Protein likely involved in protection against replication-dependent DNA damage: mutants are sensitive to methyl methanesulfonate (MMS): implicated in regulation of Ty1 transposition
YLR226w BUR2 0.325
Cyclin for the Sgv1p (Bur1p) protein kinase: Sgv1p and Bur2p comprise a CDK-cyclin complex involved in transcriptional regulation through its phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II
YNL250w RAD50 0.325
Mre11-Rad50-Xrs2 protein complex member involved in joining double-stranded breaks and DNA recombination
YOR198c BFR1 0.327
Multicopy suppressor of BFA (Brefeldin A)-induced lethality; implicated in secretion and nuclear segregation
YNL133c FYV6 0.329
Protein of unknown function, required for survival upon exposure to K1 killer toxin; proposed to regulate double-strand break repair via non-homologous end-joining
YHR154w RTT107 0.329
Regulator of Ty1 Transposition; Establishes Silent Chromatin
YPL129w TAF14 0.329
Subunit (30 kDa) of TFIID, TFIIF, and SWI/SNF complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, contains a YEATS domain
YKL204w EAP1 0.334
eIF4E-associated protein, binds eIF4E and inhibits cap-dependent translation, also functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade
YOL076w MDM20 0.339
Subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met
YLR318w EST2 0.340
Reverse transcriptase subunit of the telomerase holoenzyme, essential for telomerase core catalytic activity, involved in other aspects of telomerase assembly and function
YGR122w 0.341
Hypothetical ORF
YBL094c 0.342
Hypothetical ORF
YDR335w MSN5 0.343
Karyopherin involved in nuclear import and export; shown to be responsible for nuclear import of replication protein A and for export of several proteins including Swi6p, Far1p, and Pho4p; cargo dissociation involves binding to RanGTP
YDL013w HEX3 0.348
Ring finger protein involved in the DNA damage response with possible recombination role: genetically identified by synthetic lethality with SGS1 (DNA helicase) and TOP3 (DNA topoisomerase): sporulation role: interacts with Slx8p and Lin1p
YCR002c CDC10 0.350
septin
YER095w RAD51 0.351
Rad51p colocalizes to ~ 65 spots with Dmc1p prior to synapsis (independently of ZIP1 and DMC1), and interacts with Rad52p and Rad55p; human Rad51p homolog interacts with Brca2 protein which has been implicated in causing breast cancer|RecA homolog
YOR080w DIA2 0.351
Protein of unknown function, involved in invasive and pseudohyphal growth
YDR159w SAC3 0.352
A component of the nuclear pore that is involved in the nuclear export of both mRNA and protein
YML032c RAD52 0.354
Protein that stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis
YLL002w RTT109 0.354
Regulator of Ty1 Transposition; Regulation of mitochondrial network; Killed in Mutagen, sensitive to diepoxybutane and/or mitomycin C
YNL171c 0.358
Hypothetical ORF
YCR066w RAD18 0.358
ATPase (putative)|zinc finger protein
YLR358c 0.367
Hypothetical ORF
YDR369c XRS2 0.367
DNA repair protein
YGL163c RAD54 0.381
DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family
YMR078c CTF18 0.384
Subunit of a complex with Ctf8p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion; may have overlapping functions with Rad24p in the DNA damage replication checkpoint
YJL080c SCP160 0.388
May be required during cell division for faithful partitioning of the ER-nuclear envelope membranes, involved in control of mitotic chromsome transmission
YHR191c CTF8 0.406
Subunit of a complex with Ctf18p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion
YDR300c PRO1 0.409
gamma-glutamyl kinase
YBR112c CYC8 0.409
General transcriptional co-repressor, acts together with Tup1p: also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters
YLR233c EST1 0.411
Telomere elongation protein
YPR135w CTF4 0.427
DNA polymerase alpha binding protein
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