SCMD Saccharomyces Cerevisiae Morphological Database
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Keywords: (ex. rad52, polarisome)

Sortable ORF Parameter Sheet

Parameter Name:D16-3_C
Stain Type:Nucleus
Nucleus Status:C
Parameter Type:Average
Description:Maximum brightness of nuclei
Definition:Maximum brightness of nuclei
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ORF Std. Name D16-3_C
YKL113c RAD27 196
42 kDa 5' to 3' exonuclease required for Okazaki fragment processing
YIL093c RSM25 196
mitochondrial ribosome small subunit component
YIL108w 198
Hypothetical ORF
YDR364c CDC40 198
Pre-mRNA splicing factor, important for catalytic step II of pre-mRNA splicing and plays a role in cell cycle progression: required for DNA synthesis during mitosis and meiosis: has WD repeats
YKL126w YPK1 199
Serine/threonine protein kinase required for receptor-mediated endocytosis: involved in sphingolipid-mediated and cell integrity signaling pathways: localized to the bud neck, cytosol and plasma membrane: homolog of mammalian kinase SGK
YNL264c PDR17 199
Pdr16p homolog|Sec14p homolog
YHR057c CPR2 199
cyclophilin|peptidyl-prolyl cis-trans isomerase (PPIase)
YER070w RNR1 200
Ribonucleotide-diphosphate reductase (RNR), large subunit: the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits
YDL013w HEX3 202
Ring finger protein involved in the DNA damage response with possible recombination role: genetically identified by synthetic lethality with SGS1 (DNA helicase) and TOP3 (DNA topoisomerase): sporulation role: interacts with Slx8p and Lin1p
YFR048w RMD8 203
Cytosolic protein required for sporulation
YOR202w HIS3 203
Imidazoleglycerol-phosphate dehydratase, catalyzes the sixth step in histidine biosynthesis: mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts: transcription is regulated by general amino acid control via Gcn4p
YAL047c SPC72 203
Spc72p interacts with Stu2p in the two-hybrid assay; Spc72p localizes to the spindle pole bodies. Molecular weight is 72 kD
YDL021w GPM2 205
Similar to GPM1 (phosphoglycerate mutase); converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis
YOR323c PRO2 206
gamma-glutamyl phosphate reductase
YMR148w 206
Hypothetical ORF
YJL192c SOP4 210
suppressor of pma1-7
YHR158c KEL1 211
Protein required for proper cell fusion and cell morphology; functions in a complex with Kel2p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate
YMR116c ASC1 212
WD repeat protein (G-beta like protein) involved in translation regulation: required for repression of Gcn4p activity in the absence of amino-acid starvation: core component of the ribosome: ortholog of mammalian RACK1
YAL066w 214
Hypothetical ORF
YAR035w YAT1 215
carnitine acetyltransferase
YNL148c ALF1 216
tubulin folding cofactor B
YMR190c SGS1 217
Nucleolar DNA helicase of the RecQ family, involved in maintenance of genome integrity; has similarity to human BLM and WRN helicases implicated in Bloom and Werner syndromes
YDL169c UGX2 218
Protein of unknown function
YNR061c 219
Hypothetical ORF
YML032c RAD52 221
Protein that stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis
YDR290w 221
Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 42% of ORF overlaps the verified gene RTT103; deletion causes hydroxyuracil sensitivity
YPR141c KAR3 222
Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating: potential Cdc28p substrate
YMR025w CSI1 222
Interactor with COP9 signalosome (CSN) complex
YNL093w YPT53 228
GTP-binding protein|rab family
YDR129c SAC6 231
actin filament bundling protein|fimbrin homolog
YIL067c 231
Hypothetical ORF
YMR198w CIK1 233
Kar3-binding protein
YMR014w BUD22 233
Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
YER019w ISC1 235
ISC1 encodes phospholipase C type enzyme which hydrolyzes inositolphosphosphingolipids (IPC, MIPC, M(IP)2C) as well as sphingomyelin.
YPL055c LGE1 245
Protein of unknown function; null mutant forms abnormally large cells
YCR002c CDC10 247
septin
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