| ORF |
Std. Name |
|
A7-2_A1B |
|
YKL126w
|
YPK1 |
|
306
|
| Serine/threonine protein kinase required for receptor-mediated endocytosis: involved in sphingolipid-mediated and cell integrity signaling pathways: localized to the bud neck, cytosol and plasma membrane: homolog of mammalian kinase SGK |
|
YCR002c
|
CDC10 |
|
308
|
| septin |
|
YMR185w
|
|
|
308
|
| Protein required for cell viability |
|
YDR264c
|
AKR1 |
|
312
|
| ankyrin repeat-containing protein |
|
YIL121w
|
|
|
313
|
| plasma membrane transporter |
|
YOR198c
|
BFR1 |
|
314
|
| Multicopy suppressor of BFA (Brefeldin A)-induced lethality; implicated in secretion and nuclear segregation |
|
YLR021w
|
|
|
315
|
| Hypothetical ORF |
|
YBR112c
|
CYC8 |
|
317
|
| General transcriptional co-repressor, acts together with Tup1p: also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters |
|
YDR369c
|
XRS2 |
|
317
|
| DNA repair protein |
|
YGL163c
|
RAD54 |
|
321
|
| DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family |
|
YER070w
|
RNR1 |
|
324
|
| Ribonucleotide-diphosphate reductase (RNR), large subunit: the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits |
|
YLR399c
|
BDF1 |
|
325
|
| Required for sporulation, possible component of chromatin; affects synthesis of snRNA |
|
YKL054c
|
DEF1 |
|
326
|
| Rad26-interacting protein |
|
YMR014w
|
BUD22 |
|
327
|
| Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern |
|
YMR032w
|
HOF1 |
|
327
|
| Bud neck-localized, SH3 domain-containing protein required for cytokinesis: regulates actomyosin ring dynamics and septin localization: interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p |
|
YPR163c
|
TIF3 |
|
330
|
| translation initiation factor eIF-4B |
|
YDL116w
|
NUP84 |
|
330
|
| nuclear pore complex subunit|similar to mammalian Nup107p |
|
YLL002w
|
RTT109 |
|
331
|
| Regulator of Ty1 Transposition; Regulation of mitochondrial network; Killed in Mutagen, sensitive to diepoxybutane and/or mitomycin C |
|
YGL206c
|
CHC1 |
|
331
|
| vesicle coat protein: presumed vesicle coat protein |
|
YOR258w
|
HNT3 |
|
332
|
| Member of the third branch of the histidine triad (HIT) superfamily of nucleotide-binding proteins; similar to Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia |
|
YLR322w
|
VPS65 |
|
332
|
| Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 75% of ORF overlaps the verified gene SFH1; deletion causes a vacuolar protein sorting defect |
|
YJL140w
|
RPB4 |
|
336
|
| RNA polymerase II subunit B32: forms two subunit dissociable complex with Rpb7p: dispensable under some environmental conditions: involved in export of mRNA to cytoplasm under stress conditions |
|
YML032c
|
RAD52 |
|
338
|
| Protein that stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis |
|
YHR031c
|
RRM3 |
|
338
|
| DNA helicase |
|
YKL113c
|
RAD27 |
|
340
|
| 42 kDa 5' to 3' exonuclease required for Okazaki fragment processing |
|
YHR191c
|
CTF8 |
|
344
|
| Subunit of a complex with Ctf18p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion |
|
YDR159w
|
SAC3 |
|
351
|
| A component of the nuclear pore that is involved in the nuclear export of both mRNA and protein |
|
YCR020w-B
|
HTL1 |
|
352
|
| High-Temperature Lethal |
|
YKL204w
|
EAP1 |
|
352
|
| eIF4E-associated protein, binds eIF4E and inhibits cap-dependent translation, also functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade |
|
YOR241w
|
MET7 |
|
358
|
| Folylpolyglutamate synthetase, catalyzes extension of the glutamate chains of the folate coenzymes, required for methionine synthesis and for maintenance of mitochondrial DNA, present in both the cytoplasm and mitochondria |
|
YJL115w
|
ASF1 |
|
360
|
| anti-silencing protein that causes depression of silent loci when overexpressed |
|
YLR233c
|
EST1 |
|
361
|
| Telomere elongation protein |
|
YDR138w
|
HPR1 |
|
400
|
| Subunit of THO/TREX, related complexes that couple transcription elongation with mitotic recombination and elongation with mRNA metabolism and export, subunit of an RNA Pol II complex; regulates lifespan; similar to Top1p |
|
YPR135w
|
CTF4 |
|
413
|
| DNA polymerase alpha binding protein |
|
YOR080w
|
DIA2 |
|
500
|
| Protein of unknown function, involved in invasive and pseudohyphal growth |
|
YJL080c
|
SCP160 |
|
519
|
| May be required during cell division for faithful partitioning of the ER-nuclear envelope membranes, involved in control of mitotic chromsome transmission |
