ORF |
Std. Name |
|
A7-2_A1B |
YKL126w
|
YPK1 |
|
306
|
Serine/threonine protein kinase required for receptor-mediated endocytosis: involved in sphingolipid-mediated and cell integrity signaling pathways: localized to the bud neck, cytosol and plasma membrane: homolog of mammalian kinase SGK |
YCR002c
|
CDC10 |
|
308
|
septin |
YMR185w
|
|
|
308
|
Protein required for cell viability |
YDR264c
|
AKR1 |
|
312
|
ankyrin repeat-containing protein |
YIL121w
|
|
|
313
|
plasma membrane transporter |
YOR198c
|
BFR1 |
|
314
|
Multicopy suppressor of BFA (Brefeldin A)-induced lethality; implicated in secretion and nuclear segregation |
YLR021w
|
|
|
315
|
Hypothetical ORF |
YBR112c
|
CYC8 |
|
317
|
General transcriptional co-repressor, acts together with Tup1p: also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters |
YDR369c
|
XRS2 |
|
317
|
DNA repair protein |
YGL163c
|
RAD54 |
|
321
|
DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family |
YER070w
|
RNR1 |
|
324
|
Ribonucleotide-diphosphate reductase (RNR), large subunit: the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits |
YLR399c
|
BDF1 |
|
325
|
Required for sporulation, possible component of chromatin; affects synthesis of snRNA |
YKL054c
|
DEF1 |
|
326
|
Rad26-interacting protein |
YMR014w
|
BUD22 |
|
327
|
Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern |
YMR032w
|
HOF1 |
|
327
|
Bud neck-localized, SH3 domain-containing protein required for cytokinesis: regulates actomyosin ring dynamics and septin localization: interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p |
YPR163c
|
TIF3 |
|
330
|
translation initiation factor eIF-4B |
YDL116w
|
NUP84 |
|
330
|
nuclear pore complex subunit|similar to mammalian Nup107p |
YLL002w
|
RTT109 |
|
331
|
Regulator of Ty1 Transposition; Regulation of mitochondrial network; Killed in Mutagen, sensitive to diepoxybutane and/or mitomycin C |
YGL206c
|
CHC1 |
|
331
|
vesicle coat protein: presumed vesicle coat protein |
YOR258w
|
HNT3 |
|
332
|
Member of the third branch of the histidine triad (HIT) superfamily of nucleotide-binding proteins; similar to Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia |
YLR322w
|
VPS65 |
|
332
|
Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 75% of ORF overlaps the verified gene SFH1; deletion causes a vacuolar protein sorting defect |
YJL140w
|
RPB4 |
|
336
|
RNA polymerase II subunit B32: forms two subunit dissociable complex with Rpb7p: dispensable under some environmental conditions: involved in export of mRNA to cytoplasm under stress conditions |
YML032c
|
RAD52 |
|
338
|
Protein that stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis |
YHR031c
|
RRM3 |
|
338
|
DNA helicase |
YKL113c
|
RAD27 |
|
340
|
42 kDa 5' to 3' exonuclease required for Okazaki fragment processing |
YHR191c
|
CTF8 |
|
344
|
Subunit of a complex with Ctf18p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion |
YDR159w
|
SAC3 |
|
351
|
A component of the nuclear pore that is involved in the nuclear export of both mRNA and protein |
YCR020w-B
|
HTL1 |
|
352
|
High-Temperature Lethal |
YKL204w
|
EAP1 |
|
352
|
eIF4E-associated protein, binds eIF4E and inhibits cap-dependent translation, also functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade |
YOR241w
|
MET7 |
|
358
|
Folylpolyglutamate synthetase, catalyzes extension of the glutamate chains of the folate coenzymes, required for methionine synthesis and for maintenance of mitochondrial DNA, present in both the cytoplasm and mitochondria |
YJL115w
|
ASF1 |
|
360
|
anti-silencing protein that causes depression of silent loci when overexpressed |
YLR233c
|
EST1 |
|
361
|
Telomere elongation protein |
YDR138w
|
HPR1 |
|
400
|
Subunit of THO/TREX, related complexes that couple transcription elongation with mitotic recombination and elongation with mRNA metabolism and export, subunit of an RNA Pol II complex; regulates lifespan; similar to Top1p |
YPR135w
|
CTF4 |
|
413
|
DNA polymerase alpha binding protein |
YOR080w
|
DIA2 |
|
500
|
Protein of unknown function, involved in invasive and pseudohyphal growth |
YJL080c
|
SCP160 |
|
519
|
May be required during cell division for faithful partitioning of the ER-nuclear envelope membranes, involved in control of mitotic chromsome transmission |