SCMD Saccharomyces Cerevisiae Morphological Database
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Keywords: (ex. rad52, polarisome)

Sortable ORF Parameter Sheet

Parameter Name:CCV13_A
Stain Type:Cell Wall
Nucleus Status:A
Parameter Type:Coefficient of Variation
Description:Fitness in nucleus A
Definition:Fitness in nucleus A
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ORF Std. Name CCV13_A
YMR014w BUD22 0.269
Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
YHR031c RRM3 0.277
DNA helicase
YOL115w TRF4 0.279
DNA polymerase sigma
YNL138w SRV2 0.283
70 kDa adenylyl cyclase-associated protein
YJR063w RPA12 0.288
RNA polymerase I subunit A12.2: contains two zinc binding domains, and the N terminal domain is responsible for anchoring to the RNA pol I complex
YBR279w PAF1 0.299
RNA polymerase II-associated protein, defines a large complex that is biochemically and functionally distinct from the Srb-Mediator form of Pol II holoenzyme and is required for full expression of a subset of cell cycle-regulated genes
YPR141c KAR3 0.300
Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating: potential Cdc28p substrate
YIL121w 0.301
plasma membrane transporter
YCL014w BUD3 0.306
Protein involved in bud-site selection and required for axial budding pattern: localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding
YDL006w PTC1 0.307
Type 2C protein phosphatase (PP2C): inactivates the osmosensing MAPK cascade by dephosphorylating Hog1p: mutation delays mitochondrial inheritance: deletion reveals defects in precursor tRNA splicing, sporulation and cell separation
YDL073w 0.320
Hypothetical ORF
YDL042c SIR2 0.324
Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespan: plays roles in silencing at HML, HMR, telomeres, and the rDNA locus: negatively regulates initiation of DNA replication
YER070w RNR1 0.327
Ribonucleotide-diphosphate reductase (RNR), large subunit: the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits
YBR085w AAC3 0.329
Mitochondrial inner membrane ADP/ATP translocator, exchanges cytosolic ADP for mitochondrially synthesized ATP: expressed under anaerobic conditions: similar to Pet9p and Aac1p: has roles in maintenance of viability and in respiration
YJL023c PET130 0.330
Protein required for respiratory growth
YJR043c POL32 0.331
55 kDa|DNA polymerase delta subunit
YMR100w MUB1 0.331
Homolog of samB gene of Aspergillus nidulans (deletion of samB results in mislocalization of septa
YGR062c COX18 0.332
Mitochondrial inner membrane protein, required for export of the Cox2p C terminus from the mitochondrial matrix to the intermembrane space during its assembly into cytochrome c oxidase; similar to Oxa2p of N.crassa
YIL140w AXL2 0.334
Integral plasma membrane protein required for axial budding in haploid cells, localizes to the incipient bud site and bud neck: glycosylated by Pmt4p: potential Cdc28p substrate
YPR043w RPL43A 0.335
ribosomal protein L43A
YLL030c 0.335
Hypothetical ORF
YHR193c EGD2 0.336
GAL4 enhancer protein|nascent-polypeptide-associated complex human alpha NAC subunit homolog
YLL020c 0.338
Hypothetical ORF
YML008c ERG6 0.339
Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol in the ergosterol biosynthetic pathway by methylating position C-24
YKL054c DEF1 0.339
Rad26-interacting protein
YOL015w 0.340
Hypothetical ORF
YBR133c HSL7 0.341
Has homology to arginine methyltransferases
YDR153c ENT5 0.342
Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p, clathrin adaptor complex AP-1, and clathrin
YDR192c NUP42 0.343
Subunit of the nuclear pore complex (NPC) that localizes exclusively to the cytoplasmic side: involved in RNA export, most likely at a terminal step: interacts with Gle1p
YPL167c REV3 0.345
DNA polymerase zeta subunit
YHR013c ARD1 0.345
N alpha-acetyltransferase major subunit|complexes with Nat1p
YNR075w COS10 0.345
Protein of unknown function, member of a family of conserved, often subtelomerically-encoded proteins
YGL085w 0.346
Hypothetical ORF
YBR162w-A YSY6 0.346
Protein that participates in secretory pathway
YMR262w 0.347
Hypothetical ORF
YDL162c 0.348
Hypothetical ORF
YOR156c NFI1 0.348
SUMO ligase, catalyzes the covalent attachment of SUMO (Smt3p) to proteins
YIL047c SYG1 0.349
plasma membrane protein
YAL066w 0.350
Hypothetical ORF
YKL007w CAP1 0.350
capping protein
YMR032w HOF1 0.350
Bud neck-localized, SH3 domain-containing protein required for cytokinesis: regulates actomyosin ring dynamics and septin localization: interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p
YPL013c MRPS16 0.351
Mitochondrial ribosomal protein of the small subunit
YMR175w SIP18 0.351
Salt-Induced Protein
YDR335w MSN5 0.352
Karyopherin involved in nuclear import and export; shown to be responsible for nuclear import of replication protein A and for export of several proteins including Swi6p, Far1p, and Pho4p; cargo dissociation involves binding to RanGTP
YKL085w MDH1 0.354
malate dehydrogenase
YBR177c EHT1 0.355
alcohol acyl transferase
YCR088w ABP1 0.355
actin binding protein
YAL053w 0.355
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
YDR323c PEP7 0.356
three zinc fingers; cysteine rich regions of amino acids are essential for function
YOR021c 0.356
Hypothetical ORF
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