SCMD Saccharomyces Cerevisiae Morphological Database
Keywords: (ex. rad52, polarisome)
Data Release Policy

We (the Saccharomyces Cerevisiae Morphological Database project) herein make a collection of micrographs, processed images, and morphological parameter values of yeast mutants publicly available by providing image browsing and data mining functions before scientific publication. We reserve the exclusive right to publish, in a timely manner, the comprehensive analysis of all the data in the SCMD. Reserved analyses include the overall statistics of morphological parameters, and the comprehensive analysis of correlations between morphological parameters and other biological data such as gene ontology categories, gene expressions, gene localizations, and gene interactions. All users may search and use the SCMD database freely under the restrictions of the previous paragraph. Since the current version is still a preliminary one and may contain mistakes, users should use the data at their own risk and are not allowed to redistribute or repackage the data.

When users publish the analysis of individual genes using the data of this site, they should include the acknowledgement "The SCMD database has been provided freely by the University of Tokyo for use in this publication/correspondence only."

Finally, we are continuing to improve the SCMD database; therefore, any feedback information from the users should be highly welcomed.

Materials
Mutants with altered cell morphology were screened from a set of the haploid MATa deleted strains obtained from EUROSCARF. Each strain was grown in YPD, harvested, stained and used for computational morphological analysis. For obtaining fluoresent images of the cell surface mannoprotein, actin cytoskeleton and nuclear DNA, cells were triply stained with FITC-ConA, rhodamine-phalloidin and DAPI.
Core Members
Ohya Laboratory (homepage) Morishita Laboratory (homepage)
Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo.

Department of Computational Biology, Graduate School of Frontier Science, University of Tokyo.


  • Postdoctroal Fellows
    • Satoru Nogami

  • Graduate Students
    • Shinsuke Ohnuki
  • Graduate Students
    • Yoichiro Nakatani
      • statistical analysis & data mining
    • Taro L. Saito
      • database program & web site management
    • Hiroshi Hatsuda
      • image processing & data mining
    • Secretary
      • Tsurutsuki Iijima
Ex-members
Miwaka Ohtani, Hiroshi Sawai, Ayaka Saka, Daisuke Watanabe, Mitsuhiro Abe, Yuri Nagai, Kouichiro Doi, Tomoyuki Yamada, Masahiro Kasahara, Emi Shimoi, Tamao Goto, Yuka Kitamura, Shin Sasaki, Naoko Bando, Yukinobu Nagayasu, Eri Nakamura, Ahsan Budrul, Wei Qu, Fumi Sano, Masashi Yukawa, Jun Sese, Genjiro Suzuki, Keiko Kono, Mieko Higuchi, Satoshi Ishihara, Aiko Hirata
Acknowledgments
This research has been partly supported by the Institute for Bioinformatics and Research and Development (BIRD) of the Japan Science and Technology Corporation (JST).